April 7, 2017

Highlights
  •Crystal structure of a new lacto-N-biosidase (LnbX) from B. longum is presented
  •The mechanism of LnbX is distinct from the lacto-N-biosidase of B. bifidum
  •lnbX is indispensable for growth and occupancy in the breast-fed infant gut
  •Host and microbe symbiotic and co-evolutionary relationships are revealed

For details, please refer to the following link
   http://www.sciencedirect.com/science/article/pii/S2451945617300958
   http://www.a.u-tokyo.ac.jp/topics/2017/20170404-1.html (Japanese)

Paper Information

Authors
Chihaya Yamada1, 2, 8, Aina Gotoh2, 8, Mikiyasu Sakanaka3, Mitchell Hattie4, Keith A. Stubbs4, Ayako Katayama-Ikegami3, Junko Hirose5, Shin Kurihara3, Takatoshi Arakawa1, Motomitsu Kitaoka6,

Author Affiliations
1 Department of Biotechnology, The University of Tokyo, Tokyo 113-8657, Japan
2 Graduate School of Biostudies, Kyoto University, Kyoto 606-8052, Japan
3 Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University, Ishikawa 921-8836, Japan
4 School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia
5 School of Human Cultures, The University of Shiga Prefecture, Hikone, Shiga 522-8533, Japan
6 Food Research Institute, National Agriculture and Food Research Organization, Ibaraki 305-8642, Japan
7 Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan

DOI: 10.1016/j.chembiol.2017.03.012
http://www.sciencedirect.com/science/article/pii/S2451945617300958

 

 

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