May 18, 2017

Nutrient signalling integrates and coordinates gene expression, metabolism and growth. However, its primary molecular mechanisms remain incompletely understood in plants and animals. Here we report unique Ca2+ signalling triggered by nitrate with live imaging of an ultrasensitive biosensor in Arabidopsis leaves and roots. ……

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Paper Information

Kun-hsiang Liu*1*2, Yajie Niu*1, Mineko Konishi*3, Yue Wu*1, Hao Du*1, Hoo Sun Chung*1, Lei Li*1, Marie Boudsocq*1*4, Matthew McCormack*1, Shugo Maekawa*3, Tetsuya Ishida*3, Chao Zhang*5, Kevan Shokat*5, Shuichi Yanagisawa *3 & Jen Sheen*1

Author Affiliations
*1 Department of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
*2 Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China
*3 Biotechnology Research Center, The University of Tokyo, Bunkyo-ku, Tokyo , Japan
*4 Institute of Plant Sciences Paris-Saclay (IPS2), CNRS, INRA, Université Paris-Sud, Université d'Evry Val d’Essonne, Université Paris-Diderot, Sorbonne Paris-Cité, Université Paris-Saclay, Orsay, France
*5 Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California , USA

DOI: 10.1038/nature22077