Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan
Shin Murakami*, Tomoya Kitamura, Jin Suzuki, Ryouta Sato, Toshiki Aoi, Marina Fujii, Hiromichi Matsugo, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Masayuki Shimojima, Taisuke Horimoto*
Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.
- : Emerging Infectious Diseases
- : DOI: 10.3201/eid2612.203386
- : https://wwwnc.cdc.gov/eid/article/26/12/20-3386_article