Mast cell–derived prostaglandin D2 attenuates anaphylactic reactions in mice
April 28, 2017
Anaphylaxis is a severe and life-threatening allergic reaction. As of the last decade, 0.05% to 2% of the general population worldwide experienced an anaphylactic reaction during their lifetime, and approximately 2% of these subjects died as a result of the reaction.……
For details, please refer to the following link
http://www.jacionline.org/article/S0091-6749(17)30476-1/abstract
https://www.a.u-tokyo.ac.jp/topics/2017/20170428-1.html (Japanese)
Paper Information
Authors
Tatsuro Nakamura*1, DVM, PhD, Yuki Fujiwara*1, BSc, Ryota Yamada*1, BSc, Wataru Fujii*1, PhD, Taiki Hamabata*1, BSc, Monica Yunkyung Lee*2, PhD, Shingo Maeda*1, DVM, PhD, Kosuke Aritake*3, PhD, Axel Roers*4, MD, PhD, William C. Sessa*2, PhD, Masataka Nakamura*5, PhD, Yoshihiro Urade*4, PhD, Takahisa Murata*1, DVM, PhD
Author Affiliations
*1 Graduate School of Agricultural and Life Sciences,The University of Tokyo, Tokyo,Japan
*2 Department of Pharmacology, Yale University School of Medicine, New Haven, Conn,USA
*3 International Institute for Integrative Sleep Medicine, University of Tsukuba, Ibaraki, Japan
*4 Institute for Immunology, Technische Universität Dresden, Dresden, Germany
*5 Human Gene Sciences Center, Tokyo Medical and Dental University, Tokyo, Japan
DOI: 10.1016/j.jaci.2017.02.030
http://www.jacionline.org/article/S0091-6749(17)30476-1/abstract